Advantages of BÜHLMANN GanglioCombi® MAG ELISA

The IVDR-compliant BÜHLMANN GanglioCombi® version includes Ganglioside T1a (GT1a), replacing Ganglioside M2 (Profile: «MAG», GM1, GT1a, GD1a, GD1b, GQ1b).

The BÜHLMANN GanglioCombi® MAG ELISA is the ideal and efficient tool to support investigations of autoimmune related peripheral neuropathies. It combines, as unique multiparametric IVD ELISA, MAG and ganglioside antigens on the same profile and thus enables a targeted screening for the most prominent immune-mediated neuropathies. The kit features all enzyme label-conjugates and allows for an economic, efficient and complete work-up in two steps.

Test values may be related and interpreted as 1 of 3 titre categories: negative, positive or equivocal (grey zone), which matches up with the basic concept in autoimmunology where values are rarely black or white. MAG (IgM) positive results point to putative MAG neuropathy or MGUS (monoclonal gammopathy of unknown significance) and may be confirmed with the gold standard anti-MAG Antibodies ELISA.

BÜHLMANN GanglioCombi® MAG ELISA Product Information

Method ELISA
Analytes anti-MAG* and –Ganglioside antibodies (GM1, GT1a, GD1a, GD1b, GQ1b)
Time to Result 4.5 h (approx.)
Sample type and -volume serum; 100 uL (1:50)
Enzyme-labels IgG/IgM Mix, IgM and IgG
Results % Ratio of Calibrator
Cut-off 50%
Order Code EK-GCM
CE (IVDR compliant)

* Chemically synthesized HNK-1 epitope of the MAG glycoprotein


Neuroimmunology Key Literature List is coming soon